With amino functionalization and temperature responsiveness (LCST≈32℃) as the core, PNIPAm-NH₂ empowers multiple fields:
Intelligent medical: tumor-targeted drug delivery (drug loading >20%), temperature/pH dual response trigger release; gene vector: amino-binding DNA improves transfection efficiency (adapted to CRISPR system);
Tissue engineering: 3D printed thermosensitive hydrogel scaffolds to guide cell growth; cell desorption without loss, replacing traditional enzymatic methods;
Intelligent detection: Gold nanocomposite SERS temperature probe (sensitivity 0.1℃), adaptive trace analysis.